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Adrià Mitjavila Ventura
MSc | PhD student in Bioinformatics at Institut Josep Carreras
Biotechnologist with training in Molecular Genetics and Bioinformatics. Interested in omics data analysis to study the mechanisms of gene regulation and their evolution. See more about me on my website.
Experience
PhD student
Institut Germans Trias i Pujol & Institut Josep Carreras
Badalona, Spain
11/2022 - Present
Group of Regulatory Genomics (Dr. Tanya Vavouri)
Study of the role of transposable elements in the evolution of gene regulation in mammals.
- Analysis and integration of small RNA-seq, RNA-seq and genomics data.
- Mentoring of graduate students and collegues.
- Workshops addressed to high-school students.
Bioinformatician & master’s thesis student
Badalona, Spain
08/2021 - 11/2022
Group of Regulatory Genomics (Dr. Tanya Vavouri)
Study of Piwi-interacting RNAs (piRNAs), their biogenesis mechanisms and their conservation across species.
- Analysis and integration of small RNA-seq, RNA-seq and genomics data.
- Master’s thesis (UOC): Analysis of the variation in piRNA expression across three Mus species.
- Mentoring of bachelor’s and master’s thesis students.
- Workshops addressed to high-school students.
Bioinformatician
Milan, Italy
07/2019 - 07/2021
Group of Epigenetic Mechanisms in Cancer (Dr. Diego Pasini)
Study of Wnt/\(\beta\)catenin signaling pathway -and others- and its effects in transcription and epigenetic modifications in the context of colorectal cancer and stem cell development.
- Analysis and integration of omics data (RNA-/ChIP-/ATAC-seq).
- Comparison of different ATAC-seq peak callers.
- Comparison of different sequencing depths for RNA-seq and their influence in differential expression analysis.
Master’s thesis student & Research assistant
Instituto de Biomedicina de Sevilla
Seville, Spain
09/2017 - 10/2018
Group of Gene Expression (Dr. Sebastián Chávez)
Study of Xrn1 and Ccr4 roles in yeast nucleosome architecture and gene transcription.
- Analysis of MNase-seq data and MNase-qPCR experiments from Xrn1-, Ccr4-mutant and WT yeast strains.
- Master’s thesis (US): Influence of Xrn1 in nucleosome positioning […] and its effects in transcription.
Internship student
Institut d’Investigació Biomèdica de Girona
Girona, Spain
07/2017 - 09/2017
Unit of Diabetes, Endocrinology and Nutrition
Extracurricular internship. Identification of novel factors (genetic and bacterial) related to adipose tissue physiology and obesity.
- RNA/DNA extraction from mouse hepatic biopsies and human fecal material.
Internship & bachelor’s thesis student
Microbial. Sistemes i aplicacions analítiques, S.L.
Girona, Spain
09/2016 - 06/2017
Microbiological and molecular analyses of food and water for pathogen detection and food forensics | Study of butyrate effects on the ileal microbiota of colectomized colorectal cancer patients.
- DNA extraction of intestinal mucosa biopsies.
- (q)PCR experiments to detect clusters and families of bacteria.
- Statistical analysis of NGS data to quantify bacterial genera in intestinal biopsies.
- Bachelor’s thesis (UdG): Butyrate-induced changes in the […] microbiota in colorectal cancer patients […].
Education
PhD in Bioinformatics
Universitat Autònoma de Barcelona (UAB)
Barcelona, Spain
2022 - Present
- INPhINIT Incoming PhD Fellowship from LaCaixa.
- Research carried out at Regulatory Genomics group of the Institut Josep Carreras (IJC).
- Supervisor: Dr. Tanya Vavouri.
MSc in Bioinformatics and Biostatistics
Universitat Oberta de Catalunya (UOC)
Online
2018 - 2022
- Focused on Computational Genomics.
- Master’s thesis: Analysis of the variation in piRNA expression across three close related Mus species. Grade: 9.7/10 (with honours). Supervisor: Dr. Tanya Vavouri.
- Overall grade: 8.94/10.
MSc in Molecular Genetics and Biotechnology
Universidad de Sevilla (US)
Seville, Spain
2017 - 2018
- Specialization in Molecular Biology Research.
- Master’s thesis: Influence of Xrn1 in nucleosome positioning across Saccharomyces cerevisiae genome and its effects in transcription. Grade: 9.2/10. Supervisors: Dr. Sebastián Chávez de Diego & Dr. Gabriel Gutiérrez Pozo.
- Overall grade: 9.33/10.
BSc in Biotechnology
Universitat de Girona (UdG)
Girona, Spain
2012 - 2017
- Specialization in Cellular & Molecular Biotechnology.
- Bachelor’s thesis: Butyrate-induced changes in the diversity of intestinal mucosa-associated microbiota in colorectal cancer patients submitted to a lateral ileostomy. Grade: 9.4/10. Supervisor: Prof. Jesús García-Gil.
- Overall grade: 8.12/10.
Publications
Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration
Begley et al., RNA Biology, 2021. doi: 10.1080/15476286.2020.1845504
N/A
2021
Posters & presentations
Analysis of piRNA variation across three Mus species (in Catalan)
Mitjavila & Vavouri. Presentation at the Jornades de Biologia de la Reproducció from the Societat Catalana de Biologia.
N/A
03/2022
Fast evolution of piRNA cluster expression across three mouse species.
Mitjavila & Vavouri. Poster at the Workshop of the PhD program in Bioinformatics from UAB.
N/A
02/2023